{"title":"Updated Courses With MoBi (v12)","description":"","products":[{"product_id":"maternal-fetal-pbpk-copy","title":"Maternal-Fetal PBPK","description":"\u003cspan data-mce-fragment=\"1\"\u003eIn this course, you will learn how to create a PBPK model of Metronidazole, an antibiotic against anaerobic bacteria. You will create\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e• a non-pregnant individual\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e• a non-pregnant population\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e• a pregnant population, and\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e• a PBPK model of Metronidazole.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe exercises are based on the published PBPK model of Metronidazole:\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e• Dallmann et al. 2018, Clin Pharmacokinet. 57(6): 749-768.\u003c\/span\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":55930103628107,"sku":null,"price":500.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/14_-_Maternal-Fetal.png?v=1717433561"},{"product_id":"large-molecule-pbpk-tmdd","title":"Large Molecule PBPK \u0026 TMDD","description":"\u003cp\u003e\u003cspan\u003eIn this course you will learn how to set up a simulation for large molecules (proteins and peptides) in PK-Sim, export it to MoBi, and implement a Target-Mediated Drug Disposition (TMDD) model. This is demonstrated in the context of a model for antibody-drug conjugate PK and PD.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eThe course is the first in a series of three. In the next courses \"Adding an Organ (Tumor)\" (M08-12) and \"QSP: Tumor Growth Inhibition\" (M09-12), you will also learn how to generate a tumor compartment and link its volume to a tumor growth model.\u003c\/span\u003e\u003c\/p\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":55931804320075,"sku":null,"price":400.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/Thumbnails_3_9a7ede0b-3142-4995-980b-ddc190d55f4d.png?v=1763473085"},{"product_id":"adding-an-organ-tumor","title":"Adding an Organ (Tumor)","description":"\u003cp\u003eIn this course you will learn how to generate a tumor organ from a clone of another organ (muscle). The course is the second in a series of three. In the first course \"Large Molecules PBPK \u0026amp;amp; TMDD\" (M07-12) and \"QSP: Tumor Growth Inhibition\" (M09-12), you will also learn how to set up a PBPK model for a large molecule including TMDD and how to link the tumor volume to a tumor growth model, respectively.\u003c\/p\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":55931809661259,"sku":null,"price":300.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/Thumbnails_5.png?v=1763473138"},{"product_id":"qsp-tumor-growth-inhibition","title":"QSP: Tumor Growth Inhibition","description":"\u003cp\u003eIn this course you will learn how to generate a tumor organ from a clone of another organ (muscle). The course is the second in a series of three. In the first course \"Large Molecules PBPK \u0026amp;amp; TMDD\" (M07-12) and \"QSP: Tumor Growth Inhibition\" (M09-12), you will also learn how to set up a PBPK model for a large molecule including TMDD and how to link the tumor volume to a tumor growth model, respectively.\u003c\/p\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":55931834532171,"sku":null,"price":350.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/Thumbnails_1_464d5f76-6d93-46cc-8731-dd634eabbba0.png?v=1763473350"},{"product_id":"a-two-container-model","title":"A Two Container Model","description":"\u003cspan data-mce-fragment=\"1\"\u003eIn this course, you will start with a new MoBi file from scratch. You will create two physical containers connected by a neighborhood. In those containers, two molecules will be transferred from one container to the other. You will also learn how to set up different equations.\u003c\/span\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":55997270393163,"sku":null,"price":150.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/10_-_Two_Container.png?v=1717432968"},{"product_id":"lysosomal-trapping","title":"Lysosomal Trapping","description":"In this exercise, you will learn how to extend a PBPK model by new compartments and model the distribution of compounds based on partition coefficients. You will implement a simplified model of lysosomal trapping. Lysosomes are organelles within cells with low pH (4-5) that can bind basic lipophilic molecules.","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":56332413272395,"sku":null,"price":150.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/11-LysosomalTrapping_cf2fcfdc-d345-4885-8afc-b6c188f61627.png?v=1717433431"},{"product_id":"formula-types-copy","title":"Formula Types","description":"\u003cspan\u003eYou will learn to apply different equation types (Explicit, Sum, Conditional). We will exemplarily assume a simplified circadian clearance of the antiviral medication aciclovir.\u003c\/span\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":56332431524171,"sku":null,"price":100.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/16_-_Equation.png?v=1717433196"},{"product_id":"observer-copy","title":"Observer","description":"\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eIn this exercise, you will learn how to create different types of observers and export them to PK-Sim®. \u003c\/span\u003e\u003c\/p\u003e","brand":"OSP-Suite Version 12","offers":[{"title":"Default Title","offer_id":56332470583627,"sku":null,"price":100.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0549\/1779\/1804\/files\/17_-_Observer.png?v=1717433616"}],"url":"https:\/\/shop.esqlabs.com\/collections\/updated-courses-with-mobi-v12.oembed","provider":"ESQlabs GmbH","version":"1.0","type":"link"}