PAGE Day 2: Building Scalable PBPK - QSP Models

OSP-Suite/Event

Valamar Lacroma Hotel, Dubrovnik, Croatia

June 02, 2026

9:00 am - 5:00 pm

Day 2 Workshop: Building Scalable PBPK - QSP Models

ESQlabs is excited to present four Satellite Workshop options at PAGE!
Two full-day workshops will take place on June 1, followed by two additional full-day workshops on June 2. To get the most out of the experience, choose one workshop on Day 1 and another on Day 2, creating a comprehensive learning path and maximizing your time at PAGE.

The revolutionary modularization approach introduced in V12 of  the OSP Suite significantly enhances the flexibility, scalability, and efficiency of quantitative systems pharmacology (QSP) modeling and integrations with physiologically based PK (PBPK-QSP).

This full-day hands-on workshop, "Building Scalable PBPK-QSP Models", will equip participants with the skills to leverage modular workflows in MoBi® to build, extend, and refine PBPK-QSP models like never before. 

During this advanced workshop, attendees will start with a simple two-compartment model to grasp the fundamentals of modularization before diving into a real-world case study: modeling an ADC modality for tumor treatment.

In the second part of the workshop, participants will:

Develop a PBPK model for the large molecule and small molecule payload.
Modularization 1: Add a Target-Mediated Drug Disposition reaction network as a reaction extension module.
Modularization 2: Add a tumor organ as a physiological extension module.
Modularization 3: Implement a pharmacodynamic effect extension module to simulate tumor growth inhibition.
Work with separate modules to demonstrate how modular workflows streamline model management, reuse, and extension.

Attendees will master the new modular approach in MoBi®,  learning how to efficiently build and manage complex models in a structured way. While automated model qualification will be touched upon as an outlook, the focus will be on hands-on modeling and modularization techniques that enhance collaboration, transparency, and reusability in PBPK-QSP modeling.

At the end of the workshop, you will be able to:

Understand the modularization in OSP Suite V12 
Add new organs to PBPK models seamlessly 
Develop effect models as independent modules 
Model tumor treatment and large molecules with modular PBPK-QSP workflows

Who Should Attend? This workshop is ideal for PBPK/QSP modelers, clinical pharmacologists, and researchers looking to enhance their mechanistic modeling workflows using the latest innovations in MoBi® and OSP Suite V12. Whether you're new to OSP Suite or an experienced user, you'll leave with practical skills to create modular, scalable, and reusable models for drug development and translational research. 

Prerequisite: basic knowledge in PK-Sim®, gained through hands-on experience or by attending the "Mastering PBPK with PK-Sim®" from Day 1 ESQlabs workshops at PAGE.

Instructors: Dr. Wilbert de Witte and Tatiana Zasedateleva .

The current prices reflect our early bird discount, valid until April 20.

The participation fee includes catering with a morning coffee break, lunch, and an afternoon coffee break (excluding VAT).

Seats are limited, so secure your spot early.